Research Areas‎ > ‎

Heart failure

Aging and increased life expectancy led to a rising prevalence of heart failure which, afflicting close to 15 million persons in the European Union, is the main cause of hospitalization amongst the elderly, and a leading cause of morbidity, health-resource consumption and mortality. 

In Portugal its prevalence reaches 16% in the over 80-years age group. 

Despite improvements in therapy, the mortality rate remains unacceptably high and thus research at all frontiers of heart failure is one of our research priorities. This comprises several of our goals such as to:

(1) identify biomarkers that may aid patient management, 
(2) investigate pathways of disease progression that may uncover therapeutic targets, and to 
(3) clarify the systemic involvement to improve prognosis.